This image compares three DNA sequencing technologies: Sanger sequencing, Massively Parallel DNA sequencing, and Nanopore DNA sequencing. Sanger sequencing (left) sequences 500-700 bases per reaction ...

The first DNA sequencing was performed by Sanger and co-workers in the 1970s, using a method based on the attenuation of the growing nucleotide chain with dideoxythymidine triphosphate (ddTTP). The ...

The power of artificial intelligence (AI) and advanced computing has made it possible to design genetic sequences encoding ...

April 14, 2025 – Genome Research (https://genome.org) publishes a second special issue highlighting advances in long-read sequencing applications in biology and medicine. In this second Special Issue, ...

Researchers are now exploring how to best extract and use saliva-derived DNA for long-read sequencing applications. Download ...

Scientists at Rice University have unveiled a breakthrough technique that could fundamentally change how DNA is designed for ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Scientists have developed a new technique that could change how we design DNA for ...

Nanopore technology, widely renowned for its groundbreaking applications in DNA sequencing, is now being explored by researchers as a tool in a range of applications beyond genomics. In particular, ...

Saliva is an easily accessible source of high molecular weight DNA for Oxford Nanopore long-read sequencing applications.